Emerging areas of vascular biology focus on lymphatic/blood vessel mispatterning and the regulation of endothelial cell identity. However, a fundamental question remains unanswered: Can lymphatic vessels become blood vessels in adult tissues? Leveraging a novel tissue culture model, the objective of this study was to track lymphatic endothelial cell fate over the time course of adult microvascular network remodeling.

中文翻译：

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成人微血管网络中的淋巴管到血液的血管过渡：通过自上而下的仿生模型开发方法，这一发现成为可能。

血管生物学的新兴领域集中在淋巴管/血管的错误图案化和内皮细胞特性的调控上。但是，一个基本问题仍未得到解答：淋巴管能否成为成人组织中的血管？利用新的组织培养模型，本研究的目的是追踪成人微血管网络重塑过程中淋巴管内皮细胞的命运。