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Epstein-Barr Virus Seroprevalence and Primary Infection at the University Hospital Luigi Vanvitelli of Naples from 2007 to 2017.
Intervirology ( IF 4.6 ) Pub Date : 2019-05-23 , DOI: 10.1159/000496828
Gianluigi Franci 1 , Valeria Crudele 2 , Maria Teresa Della Rocca 1 , Colombina Melardo 1 , Annalisa Chianese 1 , Emiliana Finamore 2 , Francesco Bencivenga 3 , Roberta Astorri 4 , Mariateresa Vitiello 5 , Emilia Galdiero 6 , Massimiliano Galdiero 7, 8
Affiliation  

Epstein-Barr virus (EBV) is a common herpesvirus that may cause asymptomatic infection or various diseases, such as mononucleosis, lymphoproliferative disorders and several cancers. Our objective was to estimate the prevalence of EBV among patients hospitalized in "Luigi Vanvitelli" University Hospital in the last 10 years. Our results showed that EBV seroprevalence in our geographical area was 65%. Seroprevalence increased gradually with age with no significant difference between females (49.42%) and males (50.58%). The seropositivity for primary infection was higher in patients about 5 years old, while seropositivity for past infection was predominant in patients of about 35 years old. These results underline that children in our country are still exposed to EBV. The development and the deeper use of an EBV vaccine in the early years of life could represent the solution for this infection.

中文翻译:

那不勒斯大学医院路易吉·范维特利(Luigi Vanvitelli)于2007年至2017年在爱泼斯坦-巴尔病毒的血清阳性率和原发感染中

爱泼斯坦巴尔病毒(EBV)是一种常见的疱疹病毒,可能会导致无症状感染或各种疾病,例如单核细胞增多症,淋巴增生性疾病和几种癌症。我们的目标是评估过去10年在“ Luigi Vanvitelli”大学医院住院的患者中的EBV患病率。我们的结果表明,我们地理区域中的EBV血清阳性率为65%。血清阳性率随年龄逐渐增加,女性(49.42%)和男性(50.58%)之间无显着差异。大约5岁的患者对初次感染的血清阳性率较高,而大约35岁的患者对过去感染的血清阳性率较高。这些结果表明,我们国家的儿童仍然接触EBV。
更新日期:2019-11-01
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