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Schistosomiasis control: keep taking the tablets.
Trends in Parasitology ( IF 9.6 ) Pub Date : 2004-01-30 , DOI: 10.1016/j.pt.2003.11.010
Paul Hagan 1 , Christopher C Appleton , Gerald C Coles , John R Kusel , Louis Albert Tchuem-Tchuenté
Affiliation  

Despite the limited reports of praziquantel resistance, the relative success of chemotherapy-based control programmes for schistosomiasis has prompted overdue efforts to expand the use of cheap, generic, praziquantel in sub-Saharan Africa. The likely impact of such programmes on the development and spread of praziquantel resistance is uncertain, but this possibility reinforces the need for monitoring the spectrum of praziquantel sensitivity of schistosome populations and for an improved knowledge of the precise targets for the action of the drug. The search for alternatives to praziquantel and other tools for control of schistosomiasis must continue.

中文翻译:

血吸虫病控制:继续服用药片。

尽管对吡喹酮耐药的报道很少,但基于化学疗法的血吸虫病控制计划的相对成功促使人们在撒哈拉以南非洲扩大了廉价廉价,通用吡喹酮的使用的努力。此类方案对吡喹酮耐药性发生和扩散的可能影响尚不确定,但这种可能性增加了监测血吸虫病人群对吡喹酮敏感性谱的需求以及对药物作用的确切靶标的了解有所提高。必须继续寻找吡喹酮和其他控制血吸虫病工具的替代品。
更新日期:2019-11-01
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