The completion of the Plasmodium falciparum genome sequence heralds a new era in the effort to identify all the parasite's genes along with their cellular functions. A combination of bioinformatics and experimental proof will facilitate this process. Many enzymes in metabolic processes have been identified, but several examples exist of incomplete pathways, such as the shikimate pathway. This review uses the example of the shikimate pathway to examine the application of bioinformatics to lead experimental design in post-genomic biology.

中文翻译：

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注释疟原虫基因组和the草酸酯途径的谜。

恶性疟原虫基因组序列的完成预示着一个新时代的到来，即努力确定所有寄生虫的基因及其细胞功能。生物信息学和实验证据的结合将促进这一过程。已经确定了代谢过程中的许多酶，但是存在不完整途径（例如the草酸途径）的几个例子。本文以the草酸酯途径为例，探讨了生物信息学在基因组后生物学实验设计中的应用。