Polycystic ovarian syndrome is the most common endocrine disorder in women of reproductive age. Women with this disorder exhibit an array of disorders, including oligo-ovulation, hyperandrogenism, obesity, hyperlipidemia, infertility and insulin resistance. Of the sequelae that women experience, insulin resistance is associated with the most profound long-term morbidity. Initially, treatment regimens targeted specific symptomatology in these women, such as oligomenorrhea or hirsutism. With the discovery of the common association between insulin resistance and polycystic ovarian syndrome, however, we are able to utilize a new class of systemically targeted drugs that work on many of the symptoms found in these women.

中文翻译：

---

多囊卵巢综合征的治疗方法。

多囊卵巢综合征是育龄妇女中最常见的内分泌疾病。患有这种疾病的妇女表现出一系列疾病，包括排卵少，雄激素过多，肥胖，高脂血症，不育和胰岛素抵抗。在妇女经历的后遗症中，胰岛素抵抗与最深刻的长期发病率有关。最初，治疗方案针对这些女性的特定症状，例如少经或多毛症。然而，随着胰岛素抵抗与多囊卵巢综合征之间常见关联的发现，我们能够利用一类针对这些女性中许多症状的新型全身靶向药物。