Immunodeficiency and autoimmune phenomena may occur concomitantly in the same individual. Many immune deficiency syndromes, mainly humoral defects, are associated with autoimmune disorders. Hematological manifestations, such as thrombocytopenia and hemolytic anemia, are the most common presentation, but many other autoimmune mediated conditions have also been described. Persistent antigen stimulation, due to an inherently defective immune system ability to eradicate pathogenesis is the primary cause leading to autoimmunity in patients with primary immunodeficiency states. Other factors leading to the increase incidence of autoimmune manifestion will be discussed in the present review. Treatment with intravenous gammagluobuilin may ameliorate the autoimmune disorder and bone marrow transplantation can cure both conditions.

中文翻译：

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免疫缺陷和自身免疫。

免疫缺陷和自身免疫现象可能在同一个人中同时发生。许多免疫缺陷综合症（主要是体液缺陷）与自身免疫性疾病相关。血液学表现，如血小板减少症和溶血性贫血，是最常见的表现，但也描述了许多其他自身免疫介导的疾病。持久的抗原刺激是由于免疫系统固有的缺陷，以消除发病机理是导致具有主要免疫缺陷状态的患者自身免疫的主要原因。在本综述中将讨论导致自身免疫表现增加的其他因素。静脉用gammaglulubuuilin治疗可改善自身免疫性疾病，骨髓移植可治愈这两种情况。