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Development of the Behavioral Assessment and Research System (BARS) to detect and characterize neurotoxicity in humans.
NeuroToxicology ( IF 3.4 ) Pub Date : 2003-08-06 , DOI: 10.1016/s0161-813x(03)00023-8
Diane S Rohlman 1 , Lincoln S Gimenes , David A Eckerman , Seong-Kyu Kang , Fayssal M Farahat , W Kent Anger
Affiliation  

The Behavioral Assessment and Research System (BARS) is a computer-based testing system designed to assess neurobehavioral function in humans. It was developed to provide a series or battery of neurobehavioral tests optimized for the detection of neurotoxicity in non-mainstream human populations, specifically people with limited education or literacy. Key to meeting this goal were simply-stated instructions divided into an elemental series of steps, a 9BUTTON response unit to replace the computer keyboard for responding, and spoken instructions. Modifications all underwent serial testing in target populations to successively hone the changes to be more effective. A similar process was followed when developing adjustable parameters, test reliability assessments, and when implementing these tests with populations from different cultural groups and children. The principles and experiences that guided the development of BARS should inform the development of future testing systems to ensure that the new tests can be used with non-mainstream populations, which may be increasingly subject to neurotoxic exposures.

中文翻译:

行为评估和研究系统(BARS)的开发,用于检测和表征人类的神经毒性。

行为评估和研究系统(BARS)是基于计算机的测试系统,旨在评估人类的神经行为功能。它的开发旨在提供一系列或一系列的神经行为测试,以优化非主流人群(特别是受过教育或识字的人群)的神经毒性检测。达到此目标的关键是简单说明的指令,分为一系列基本步骤,一个9BUTTON响应单元(用于代替响应的计算机键盘)和语音指令。所有的修改都在目标人群中进行了系列测试,以使变更更有效。开发可调参数,测试可靠性评估,在对来自不同文化群体和儿童的人群进行这些测试时。指导BARS开发的原则和经验应为将来测试系统的开发提供信息,以确保新测试可用于非主流人群,因为非主流人群可能会越来越多地遭受神经毒性暴露。
更新日期:2019-11-01
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