Neuropsychologists are increasingly involved in surgical candidacy evaluations and postoperative neurobehavioral assessments of patients with movement disorders, most notably those with Parkinson's disease (PD). We review here the initial studies regarding neuropsychological outcomes of deep brain stimulation (DBS) within the subthalamic nucleus (STN) for treatment of PD. Overall, these initial investigations provide preliminary support for the cognitive and neurobehavioral safety of STN DBS. Improvements in self-reported symptoms of depression and diminished verbal fluency were the most common findings, whereas changes in global cognitive abilities, memory, attention, and frontal/executive functions were inconsistent and most often described as nominal and/or transient. The generalizability of this literature is hindered by several methodological limitations, including small samples and the absence of appropriate control participants. The clinical and theoretical implications of these initial studies are highlighted and recommendations are offered to guide future research.

中文翻译：

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丘脑下核深部脑刺激在帕金森氏病中的神经心理学后遗症：一项重要综述。

神经心理学家越来越多地参与对运动障碍患者（尤其是患有帕金森氏病（PD））的患者的手术候选资格评估和术后神经行为评估。我们在这里回顾有关在丘脑下核（STN）内治疗PD的深部脑刺激（DBS）的神经心理学结果的初步研究。总体而言，这些初步研究为STN DBS的认知和神经行为安全性提供了初步支持。自我报告的抑郁症状改善和口语流利性降低是最常见的发现，而整体认知能力，记忆力，注意力和额叶/执行功能的变化则不一致，并且通常被描述为名义和/或短暂的。几种方法学的局限性阻碍了该文献的可推广性，其中包括样本量小和缺乏适当的对照参与者。这些初步研究的临床和理论意义被强调，并提供了指导未来研究的建议。