In a prospective trial assessing the effects of beta-blockers on sexual function men with coronary heart disease were randomized to a 4 month treatment with sustained release metoprolol 95 mg or placebo. A standardized and validated self-report questionnaire (KEED = Kölner Erhebungsbogen der Erektilen Dysfunktion) dealing with several aspects of sexual performance in men had to be answered at the beginning and at the end of the study. Based on 65 patients completing the study, sex life seemed unaffected by metoprolol treatment.

中文翻译：

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β受体阻滞剂对冠心病男性性能力的影响。前瞻性，随机和双盲研究。

在一项评估β-受体阻滞剂对性功能影响的前瞻性试验中，将患有冠心病的男性随机分配接受持续释放美托洛尔95 mg或安慰剂治疗4个月。在研究的开始和结束时必须回答一份涉及男性性行为多个方面的标准化且经过验证的自我报告调查表（KEED =KölnerErhebungsbogen der Erektilen Dysfunktion）。根据65位完成研究的患者，性生活似乎不受美托洛尔治疗的影响。