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Factors influencing the development of malignant hypertension in nigeria
Journal of Human Hypertension ( IF 2.7 ) Pub Date : 2000-08-30 , DOI: 10.1038/sj.jhh.1001046
Kadiri 1 , Olutade , Osobamiro
Affiliation  

Hypertension prevalence rates remain comparatively low in Nigeria, although the associated morbidity and mortality including that due to malignant hypertension (MHT) is considerable. To determine the factors that may be associated with the development of MHT we compared 74 patients with essential MHT (age 48 +/- 9 years, 59 male, blood pressure (BP) 234 +/- 31/140 +/- 17 mm Hg) with 74, age, gender and BP-matched patients with essential benign hypertension (BHT) (49 +/- 8 years, 60 male, 227 +/- 26/136 +/- 15 mm Hg). Body mass index was higher in the BHT group by 1.3 (95% Cl: 0.5 to 2.1, P < 0.01). In the subset (25 MHT, 43 BHT) in whom hypertension had been diagnosed before presentation, duration of hypertension was shorter (P < 0.05) in the MHT group. Patients with MHT, were more likely to have been receiving inadequate therapy in the months before (OR 2.7, 95% Cl: 1.4 to 5.4), showed a decreasing proportion with increasing socio-economic class (chi2 = 5.79, P < 0.02) and had been exposed to a greater degree of stress (OR 3.5, 95% Cl: 1.7 to 7. 1). Smoking (OR 1.1, 0.6 to 2.3), alcohol use (OR 0.9, 0.5 to 1.8) and contraceptive pill use (OR 0.9, 0.1 to 8.6) did not impart excess risk. MHT is associated with the underprivileged and measures aimed at raising the general awareness and the socio-economic level of the people are expected to produce a decline in the incidence of MHT. Journal of Human Hypertension (2000) 14, 171-174.

中文翻译:

尼日利亚恶性高血压发展的影响因素

尼日利亚的高血压患病率仍然较低,尽管与之相关的发病率和死亡率,包括由于恶性高血压(MHT)引起的发病率和死亡率相当高。为了确定可能与MHT发生有关的因素,我们比较了74例基本MHT患者(年龄48 +/- 9岁,男性59岁,血压(BP)234 +/- 31/140 +/- 17 mm Hg ),74位年龄,性别和BP匹配的原发性良性高血压(BHT)患者(49 +/- 8岁,60男性,227 +/- 26/136 +/- 15 mm Hg)。BHT组的体重指数较高,为1.3(95%Cl:0.5至2.1,P <0.01)。在表现之前已被诊断出高血压的亚组(25 MHT,4​​3 BHT)中,MHT组的高血压持续时间较短(P <0.05)。MHT患者 在前一个月中更有可能接受不充分的治疗(OR 2.7,95%Cl:1.4至5.4),随着社会经济阶层的增加,其比例下降(chi2 = 5.79,P <0.02),并且接触过更大程度的压力(OR 3.5,95%Cl:1.7至7。1)。吸烟(OR 1.1,0.6至2.3),饮酒(OR 0.9,0.5至1.8)和避孕药(OR 0.9,0.1至8.6)不会带来过多风险。MHT与弱势群体有关,旨在提高人们的普遍认识和人们的社会经济水平的措施有望使MHT的发病率下降。人类高血压杂志(2000)14,171-174。02),并承受更大的压力(OR 3.5,95%Cl:1.7至7。1)。吸烟(OR 1.1,0.6至2.3),饮酒(OR 0.9,0.5至1.8)和避孕药(OR 0.9,0.1至8.6)不会带来过多风险。MHT与弱势群体有关,旨在提高人们的普遍认识和人们的社会经济水平的措施有望使MHT的发病率下降。人类高血压杂志(2000)14,171-174。02),并承受更大的压力(OR 3.5,95%Cl:1.7至7。1)。吸烟(OR 1.1,0.6至2.3),饮酒(OR 0.9,0.5至1.8)和避孕药(OR 0.9,0.1至8.6)不会带来过多风险。MHT与弱势群体有关,旨在提高人们的普遍认识和人们的社会经济水平的措施有望使MHT的发病率下降。人类高血压杂志(2000)14,171-174。
更新日期:2019-11-01
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