Although the prevalence and concentrations of antibiotic resistance genes (ARGs) in aquaculture is receiving increasing scientific interest, there is little understanding of the direct sources and dissemination pathways of ARGs in marine aquaculture-reared organisms. This study investigated the dynamics of ARGs and the bacterial community throughout the rearing period in a typical marine aquaculture farm in South China. The results demonstrated that sul1 and qnrD were predominant in the sediment, and qnrD and qnrA were predominant in the intestinal tracts of shrimps. Network analysis showed that the chemical oxygen demand, total organic carbon, dissolved organic carbon, suspended solids, and total phosphorus were positively correlated with the predominant ARGs. The results of the network and source tracking analyses indicate that environmental factors and the bacterial community may drive the dissemination of ARGs dissemination in the environment and in shrimp reared by marine aquaculture, and sediment is the most direct and important medium in this dissemination. These results aid in improving our understanding of the sources, level, and dissemination of ARGs in marine aquaculture.

中文翻译：

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典型的海水养殖场中抗生素抗性基因（ARG）的污染：饲养水生生物中ARG的来源跟踪。

尽管水产养殖中抗生素抗性基因（ARG）的流行和浓度受到越来越多的科学兴趣，但对海水养殖养殖生物中ARGs的直接来源和传播途径了解甚少。这项研究调查了华南地区典型海水养殖场整个饲养期间ARGs和细菌群落的动态。结果表明，sul1和qnrD在沉积物中占主导地位，qnrD和qnrA在虾的肠道中占优势。网络分析表明，化学需氧量，总有机碳，溶解的有机碳，悬浮固体和总磷与主要的ARGs正相关。网络和来源跟踪分析的结果表明，环境因素和细菌群落可能会推动环境和海洋养殖养殖对虾中ARGs的传播，而沉积物是这种传播中最直接和最重要的媒介。这些结果有助于增进我们对海水养殖中ARG的来源，水平和传播的了解。