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The MYB‐bHLH‐WDR interferers (MBWi) epigenetically suppress the MBW's targets
Biology of the Cell ( IF 2.7 ) Pub Date : 2019-10-24 , DOI: 10.1111/boc.201900069
Cuong Thach Nguyen 1 , Gia-Buu Tran 2 , Nguyen Hoai Nguyen 3
Affiliation  

Active repressors have been evidenced to function in different plant growth and development programs including hormonal signalling pathways. In Arabidopsis, the MYB–bHLH–WDR (MBW) complex is known to regulate different phenotypic traits such as anthocyanin biosynthesis, seed coat colour, trichome and root hair patterning. A number of transcription factors have been identified to play a negative role in the regulation of these traits via the interruption of MBW formation and function. Since these transcription factors work to interfere with the MBW complex, this review suggests their general name as MBW interferers (MBWi). Recent studies have shed light on the molecular mechanism of these MBWi and this review is aiming to provide a precise view of these MBWi. Moreover, from these, a new characteristic of active repressors is also updated.

中文翻译:

MYB-bHLH-WDR 干扰物 (MBWi) 表观遗传抑制 MBW 的目标

已经证明活性阻遏物在不同的植物生长和发育程序中起作用,包括激素信号通路。在拟南芥中,已知 MYB-bHLH-WDR (MBW) 复合物可调节不同的表型性状,如花青素生物合成、种皮颜色、毛状体和根毛图案。许多转录因子已被确定通过中断 MBW 形成和功能在这些性状的调节中发挥负面作用。由于这些转录因子会干扰 MBW 复合体,因此本综述建议将它们的总称称为 MBW 干扰物 (MBWi)。最近的研究阐明了这些 MBWi 的分子机制,本综述旨在提供这些 MBWi 的精确视图。此外,从这些中,还更新了主动阻遏物的新特性。
更新日期:2019-10-24
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