Modification of DNA with reactive groups and their post-synthetic transformations are useful for labelling, imaging, bioconjugations and cross-linking with other (bio)molecules. This review summarizes the recent progress in this field and covers transformations of oxo groups, cycloadditions, conjugate additions, alkylations, cross-couplings and other reactions. Examples of applications are given and the practicability and scope of the reactions are discussed.

中文翻译：

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DNA核碱基的反应性修饰，用于标记，生物缀合和交联。

具有反应性基团的DNA修饰及其合成后的转化可用于标记，成像，生物偶联以及与其他（生物）分子的交联。这篇综述总结了该领域的最新进展，并涵盖了羰基的转化，环加成，共轭加成，烷基化，交叉偶联和其他反应。给出了应用实例，并讨论了反应的实用性和范围。