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TIMP3 gene polymorphisms and relation to Ankylosing spondylitis susceptibility in Chinese Han population
International Journal of Immunogenetics ( IF 2.2 ) Pub Date : 2019-08-09 , DOI: 10.1111/iji.12453
Jiamin Wu 1 , Zichao Xiong 1 , Yao Sun 1 , Jiangjiang Song 1 , Fanglin Niu 1 , Mengdan Yan 1 , Tianbo Jin 1
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Ankylosing spondylitis (AS) is a type of chronic progressive inflammatory disease, which often causes significant damage to the patients on the physical function, labour ability and quality of life. The study found that the enzyme system tissue inhibitor of matrix metalloproteinases (TIMPs) was important for the development of AS. The aim of this study was to investigate the association of polymorphisms of TIMP3 gene with AS in Chinese Han population.
更新日期:2019-08-09
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