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Nutrigenomics in livestock-recent advances.
Journal of Applied Genetics ( IF 2.4 ) Pub Date : 2019-10-31 , DOI: 10.1007/s13353-019-00522-x
Joanna Nowacka-Woszuk 1
Affiliation  

The study of the effects of nutrients on genome functioning, in terms of gene transcription, protein levels, and epigenetic mechanisms, is referred to as nutrigenomics. Nutrigenomic studies in farm animals, as distinct from rodents, are limited by the high cost of keeping livestock, their long generational distance, and ethical aspects. Yet farm animals, and particularly pigs, can serve as valuable animal models for human gastrological diseases, since they possess similar size, physiology, and nutritional habits and can develop similar pathological states. In livestock, the effects of dietary modifications have mostly been studied with reference to effective breeding and their influence on production traits and animal health. The majority of such studies have looked at the impact of various sources and quantities of fat and protein, supplementation with microelements, and plant-derived additives. The period of life of the animal—whether prenatal, neonatal, or mature—is typically considered when a modified diet is used. This review presents a summary of recent nutrigenomic studies in livestock.

中文翻译:

畜牧业方面的营养基因组学。

就基因转录,蛋白质水平和表观遗传机制而言,研究营养素对基因组功能的影响称为营养经济学。与啮齿类动物不同,农场动物的营养基因组学研究受到饲养牲畜的高昂费用,它们长的世代相距以及道德方面的限制。然而,农场动物,特别是猪,可以作为人类胃病的有价值的动物模型,因为它们具有相似的大小,生理和营养习惯,并且可以发展出相似的病理状态。在牲畜中,大多数饮食结构改良的影响已参考有效育种及其对生产性状和动物健康的影响进行了研究。大多数此类研究都着眼于各种来源和数量的脂肪和蛋白质的影响,补充微量元素和植物来源的添加剂。当使用改良饮食时,通常会考虑动物的生命周期(无论是产前,新生儿还是成熟)。这篇综述总结了最近在牲畜上的营养学研究。
更新日期:2019-10-31
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