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Alternatives to Opioid Analgesia in Small Animal Anesthesia: Alpha-2 Agonists.
Veterinary Clinics of North America: Small Animal Practice ( IF 1.9 ) Pub Date : 2019-09-05 , DOI: 10.1016/j.cvsm.2019.07.010
Alexander Valverde 1 , Alicia M Skelding 2
Affiliation  

Alpha-2 agonists have potent analgesic effects, in addition to their sedative actions. Alpha-2 agonists provide analgesia through any of several routes of administration, including parenteral, oral, epidural or intrathecal and intraarticular, because of spinal and supraspinal actions. Systemic doses are short acting, whereas local administration at the site of action result in longer analgesic effects. The potent cardiovascular and respiratory effects of alpha-2 agonists should be considered when used as analgesics.

中文翻译:

小动物麻醉中阿片类镇痛的替代方法:Alpha-2激动剂。

Alpha-2激动剂除了具有镇静作用外,还具有有效的镇痛作用。由于脊柱和脊髓上的作用,Alpha-2激动剂通过几种给药途径中的任何一种来提供镇痛作用,包括肠胃外,口服,硬膜外或鞘内和关节内给药。全身剂量起短效作用,而在作用部位局部给药可产生更长的止痛作用。当用作镇痛药时,应考虑α-2激动剂的强力心血管和呼吸作用。
更新日期:2019-11-01
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