The primary objective was twofold: (1) to determine whether the German version of a screening instrument for clinical practice for juvenile idiopathic arthritis (SICJIA) is reliable in identifying patients at risk for juvenile idiopathic arthritis (JIA), and (2) secondly whether a weighting scheme of individual questions improves its sensitivity. Data were collected and retrospectively analyzed based upon completed SICJIA questionnaires from patients and their guardians at their first clinical visit at the Hamburg Centre for Pediatric and Adolescence Rheumatology. All patients visited the center between August 2015 and July 2017. The survey included 12 disease-orientated questions. For evaluation, only questionnaires of patients diagnosed with JIA or with a non-inflammatory joint pain (NJP) were selected. Standard statistical techniques were used for evaluation. In total, 165 of 800 questionnaires could be used for evaluation. Of the 800 patients who completed questionnaires, 133 were diagnosed with JIA and 32 with NJP. The analysis of the individual questions was performed by comparing the rate of a positive response to the questions between the two groups. Four questions showed a significant difference by comparing the groups, using JIA patients with at least one active joint. The diagnostic accuracy of the weighted sum score increased from 64 to 68% to discriminate between the groups in comparison to the ordinary sum score. An optimal cutoff of 6.0 for referral to a pediatric rheumatologist was calculated. The validation of the SICJIA showed a discriminative difference in patients with clinical diagnosed JIA and a control group diagnosed with NJP. The weighted sum score performed better to differentiate between JIA and NJP patients. The modified SICJIA can be useful to identify patients at risk of JIA.

中文翻译：

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验证并改编了德国筛查工具，以识别处于青少年特发性关节炎风险中的患者。

主要目的是双重的：（1）确定用于青少年特发性关节炎（SICJIA）临床实践的筛查工具的德语版本是否能够可靠地识别处于青少年特发性关节炎（JIA）风险的患者；以及（2）是否单个问题的加权方案可以提高其敏感性。收集数据并根据患者及其监护人在汉堡儿科和青少年风湿病学中心首次临床就诊时填写的SICJIA问卷进行回顾性分析。在2015年8月至2017年7月期间，所有患者都前往该中心。该调查包括12个针对疾病的问题。为了进行评估，仅选择诊断为JIA或患有非炎性关节痛（NJP）的患者的问卷。使用标准统计技术进行评估。总共可以使用800份问卷中的165份进行评估。在完成问卷的800名患者中，有133名被诊断为JIA，32名被诊断为NJP。通过比较两组之间对问题的肯定回答率来进行单个问题的分析。通过比较两组，使用具有至少一个活动关节的JIA患者，四个问题显示出显着差异。加权总和得分的诊断准确性与普通总和得分相比，从64％上升到68％，从而在两组之间进行区分。计算了转诊给儿科风湿病医师的最佳临界值6.0。SICJIA的验证显示，在临床诊断为JIA的患者和诊断为NJP的对照组中，存在区别。加权总和评分表现更好，可以区分JIA和NJP患者。改良的SICJIA有助于识别有JIA风险的患者。