Toxicity related to consumption of Cistus sp. pl. has been described in ruminants in some countries. This report describes the clinical and pathological findings of Cistus salviifolius toxicosis in 3 beef cattle herds located in 2 different areas of Sicily, Italy. Outbreaks were observed after grazing in poor winter pasture where C. salviifolius was abundant. Mean morbidity and mortality were 29% and 21%, respectively. Most of the affected animals (6 to 36 months old) showed anorexia, weight loss, and pollakiuria culminating in recumbency and death. Occasionally, abortion and neurological signs were observed. In animals with acute signs, there was a moderate decrease of sodium and chloride concentrations in serum. Animals with chronic signs showed an increase of serum urea, creatine phosphokinase (CPK), aspartate transaminase (AST), lactate dehydrogenase (LDH), and phosphorus and a decrease in total serum protein, calcium, chloride, and magnesium concentrations. Moderate anemia and slight neutropenia, lymphocytosis, and eosinophilia were detected in all groups. At necropsy, the main lesion was severe distention of the urinary bladder with turbid hemorrhagic urine and crystalluria. Histologically, chronic cystitis, interstitial nephritis, eosinophilic enteritis, and nonsuppurative necrotizing hepatitis were observed. To our knowledge, this is the first report of C. salviifolius toxicosis in cattle in Italy.

中文翻译：

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Cistus salviifolius对牛的毒性。

与食用Cistus sp。有关的毒性。pl。在一些国家的反刍动物中已有描述。该报告描述了位于意大利西西里岛2个不同地区的3头肉牛群中Cistus salviifolius中毒的临床和病理发现。在恶劣的冬季牧场放牧后观察到暴发，那里有丰富的C. salviifolius。平均发病率和死亡率分别为29％和21％。大多数受影响的动物（6至36个月大）表现出厌食，体重减轻和尿频，最终导致卧倒和死亡。偶尔观察到流产和神经系统症状。在有急性体征的动物中，血清中的钠和氯化物浓度有中等程度的降低。具有慢性体征的动物显示血清尿素，肌酸磷酸激酶（CPK），天冬氨酸转氨酶（AST）升高，乳酸脱氢酶（LDH）和磷，血清总蛋白，钙，氯和镁浓度降低。在所有组中均检测到中度贫血和轻度中性粒细胞减少，淋巴细胞增多和嗜酸性粒细胞增多。尸检时，主要病变是膀胱严重扩张，尿液浑浊，结晶尿。在组织学上，观察到慢性膀胱炎，间质性肾炎，嗜酸性肠炎和非化脓性坏死性肝炎。据我们所知，这是意大利牛中沙门氏菌中毒的首次报道。主要病变是膀胱严重扩张，尿液浑浊，结晶尿。在组织学上，观察到慢性膀胱炎，间质性肾炎，嗜酸性肠炎和非化脓性坏死性肝炎。据我们所知，这是意大利牛中沙门氏菌中毒的首次报道。主要病变是膀胱严重扩张，尿液浑浊，结晶尿。在组织学上，观察到慢性膀胱炎，间质性肾炎，嗜酸性肠炎和非化脓性坏死性肝炎。据我们所知，这是意大利牛中沙门氏菌中毒的首次报道。