Introduction

Decades of research have suggested that nutritional intake contributes to the development of human disease, mainly by influencing the development of obesity and obesity-related conditions. A relatively large body of research indicates that functional variation in human taste perception can influence nutritional intake as well as body mass accumulation. However, there are a considerable number of studies that suggest that no link between these variables actually exists. These discrepancies in the literature likely result from the confounding influence of a variety of other, uncontrolled, factors that can influence ingestive behavior.

Strategy

In this review, the use of controlled animal experimentation to alleviate at least some of these issues related to the lack of control of experimental variables is discussed. Specific examples of the use of some of these techniques are examined.

Discussion and conclusions

The review will close with some specific suggestions aimed at strengthening the link between gustatory neural input and its putative influence on ingestive behaviors and the maintenance of body weight.

中文翻译：

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使用动物模型确定味觉神经输入在控制摄食行为和维持体重中的作用。

介绍

数十年的研究表明，营养摄入有助于人类疾病的发展，主要是通过影响肥胖和肥胖相关疾病的发展。相对大量的研究表明，人类味觉的功能变化会影响营养摄入以及体重积累。然而，有相当多的研究表明这些变量之间实际上不存在联系。文献中的这些差异可能是由于各种其他不受控制的因素的混杂影响，这些因素会影响摄食行为。

战略

在这篇综述中，讨论了使用受控动物实验来缓解至少一些与缺乏对实验变量控制有关的问题。研究了使用其中一些技术的具体示例。

讨论和结论

审查将以一些具体建议结束，旨在加强味觉神经输入与其对摄食行为和维持体重的假定影响之间的联系。