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Insulin therapy improves islet functions by restoring pancreatic vasculature in high-fat diet-fed streptozotocin-diabetic rats.
Journal of Diabetes ( IF 4.5 ) Pub Date : 2013-11-08 , DOI: 10.1111/1753-0407.12095
Huimin Gu 1 , Xuan Xia 1 , Zonglan Chen 1 , Hua Liang 1 , Jinhua Yan 1 , Fen Xu 1 , Jianping Weng 1
Affiliation  

In a previous study, we showed early insulin therapy could improve β‐cell function in type 2 diabetic patients. However, the molecular mechanism was not clear. In the present study, we addressed this question by analyzing the pancreatic microvasculature in diabetic rats after insulin treatment.

中文翻译:

胰岛素疗法通过恢复高脂饮食喂养的链脲佐菌素-糖尿病大鼠的胰腺血管系统来改善胰岛功能。

在先前的研究中,我们显示了早期胰岛素治疗可以改善2型糖尿病患者的β细胞功能。但是,分子机制尚不清楚。在本研究中,我们通过分析胰岛素治疗后糖尿病大鼠的胰腺微血管系统解决了这个问题。
更新日期:2013-11-08
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