Tissues change in many ways in the period that they are part of a living organism. Tissues are created in fairly repeatable structural patterns, and the patterns are due to both the genes and the (mechanical) environment, but we do not know exactly what part or percentage of a particular pattern to consider the genes, or the environment, responsible for. We do not know much about the beginning of tissue construction (morphogenesis) and also the methods of tissue construction. When the tissue structure is altered to accommodate a new loading, it is not known how the decision is made for the structural reconstruction. We know that tissues grow or reconstruct themselves without ceasing to continue with their structural function, but we do not understand the processes that permit them to accomplish this. Tissues change their structures to altered mechanical environments, but we are not sure how. Tissues heal themselves and we understand little of the structural mechanics of the process. With the objective of describing the interesting unsolved mechanics problems associated with these biological processes, some aspects of the formation, growth and adaptation of living tissues are reviewed. Beyond the objective is the hope that the work will stimulate new ideas and new observations in developmental biology.

中文翻译：

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活组织的结构变化。

在它们是生物体的一部分期间，组织以多种方式发生变化。组织以相当可重复的结构模式创建，并且该模式是由于基因和（机械）环境共同导致的，但是我们不确切知道特定模式的哪个部分或百分比考虑基因或环境对。我们对组织构建（形态发生）的开始以及组织构建的方法知之甚少。当组织结构被改变以适应新的负荷时，未知如何做出结构重建的决定。我们知道组织会不断生长或重建，而不会停止继续其结构功能，但是我们不了解允许它们完成此过程的过程。组织会改变其结构以适应变化的机械环境，但我们不确定如何改变。组织会自愈，我们对该过程的结构机理了解甚少。为了描述与这些生物学过程有关的有趣的未解决的力学问题，对生物组织的形成，生长和适应性的某些方面进行了综述。超出目标的是希望这项工作将激发发育生物学的新观念和新观察。