Researchers explore the use of Bragg Ionization Peak in radiotherapy for tumors. Considerations for the production of a high quality radioactive beam include secondary beam production efficiency, primary beam survival, and multiple scattering. A Positron Emitting Beam Analyzing camera was developed and tested at BEVALAC using a neon-19 beam stopping point. Results indicate that in homogeneous brain tissues, CT measurements and radioactive beam measurements are between 1-2 mm; there can be substantial difference between CT measurements and radioactive beam estimates if the beam stopping point crosses the fossae; random coincidences due to detector activation also appear as diffused images in the image plane of the beam stopping point; and further enhancements are necessary to make reliable measurements in the human trunk and complex brain regions.

中文翻译：

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高能放射性粒子束的诊断成像：在布拉格峰癌症治疗中的应用。

研究人员探索了布拉格电离峰在肿瘤放射治疗中的用途。产生高质量放射束的考虑因素包括次束产生效率，一次束存活率和多重散射。研发了正电子发射光束分析相机，并在BEVALAC使用19氖束停止点对其进行了测试。结果表明，在均质的脑组织中，CT测量和放射性束测量在1-2 mm之间；如果射束停止点越过小窝，则CT测量值与放射性射束估计值之间可能存在实质性差异；由于检测器激活而产生的随机巧合也以散射图像的形式出现在光束停止点的图像平面中；为了在人的躯干和复杂的大脑区域进行可靠的测量，还需要进一步的增强。