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Recent advancements in two-dimensional nanomaterials for drug delivery.
WIREs Nanomedicine and Nanobiotechnology ( IF 8.6 ) Pub Date : 2019-10-25 , DOI: 10.1002/wnan.1596
Xuan Mei 1 , Tingting Hu 1 , Yingjie Wang 2 , Xisheng Weng 2 , Ruizheng Liang 1 , Min Wei 1
Affiliation  

Different from conventional zero-dimensional (0D) and one-dimensional (1D) counterparts, two-dimensional (2D) nanomaterials show unique properties resulting from their specific structure and morphology. In recent years, broad interest has been focused on the exploration of 2D nanomaterials for drug delivery, which benefits greatly to various disease treatments due to the superior properties of 2D nanomaterials. The fast development of 2D-based drug delivery systems provides great potential for biomedical studies. In this review, a case-by-case analysis was carried out on the state-of-the-art 2D nanomaterials-based drug delivery systems, which possesses great significance to the further biomedical development of 2D nanomaterials. For the purpose of discussing the special advantages of these novel drug delivery systems, this review is organized according to the different types of the latest 2D nanomaterials and their loading capacity towards various cargos. Special emphasis will be located on the application of these 2D nanomaterials-based drug delivery systems in chemotherapy, gene therapy, and immunotherapy. This article is categorized under: Therapeutic Approaches and Drug Discovery > Emerging Technologies.

中文翻译:

用于药物递送的二维纳米材料的最新进展。

与常规的零维(0D)和一维(1D)对应物不同,二维(2D)纳米材料由于其特定的结构和形态而显示出独特的特性。近年来,人们广泛关注用于药物输送的2D纳米材料的研究,由于2D纳米材料的优越性能,该方法极大地有益于各种疾病治疗。基于2D的药物输送系统的快速发展为生物医学研究提供了巨大的潜力。在这篇综述中,对基于2D纳米材料的最新药物递送系统进行了个案分析,这对2D纳米材料的进一步生物医学开发具有重要意义。为了讨论这些新型药物输送系统的特殊优势,这次审查是根据最新2D纳米材料的不同类型及其对各种货物的装载能力而组织的。这些基于2D纳米材料的药物递送系统在化学疗法,基因疗法和免疫疗法中的应用将特别受到重视。本文归类于:治疗方法和药物发现>新兴技术。
更新日期:2019-11-01
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