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ABO blood group does not impact incidence or outcomes of surgery for acute type A aortic dissection.
Scandinavian Cardiovascular Journal ( IF 2.2 ) Pub Date : 2019-10-23 , DOI: 10.1080/14017431.2019.1679387
Shahab Nozohoor 1, 2 , Khalil Ahmad 3 , Markus Bjurbom 4 , Emma C Hansson 5 , Alexandra Heimisdottir 5 , Anders Jeppsson 5 , Ari Mennander 6 , Christian Olsson 4 , Emily Pan 7 , Sigurdur Ragnarsson 1, 2 , Johan Sjögren 1, 2 , George Tellides 8 , Anders Wickbom 9 , Arnar Geirsson 8, 10 , Tomas Gudbjartsson 10 , Igor Zindovic 1, 2
Affiliation  

Objectives. To evaluate the distribution and impact of ABO blood groups on postoperative outcomes in patients undergoing surgery for acute type A aortic dissection (ATAAD). Design. A total of 1144 surgical ATAAD patients from eight Nordic centres constituting the Nordic consortium for acute type A aortic dissection (NORCAAD) were analysed. Blood group O patients were compared to non-O subjects. The relative frequency of blood groups was assessed with t-distribution, modified for weighted proportions. Multivariable logistic regression was performed to identify independent predictors of 30-day mortality. Cox regression analyses were performed for assessing independent predictors of late mortality. Results. There was no significant difference in the proportions of blood group O between the study populations in the NORCAAD registry and the background population (40.6 (95% CI 37.7-43.4)% vs 39.0 (95% CI 39.0-39.0)%). ABO blood group was not associated with any significant change in risk of 30-day or late mortality, with the exception of blood group A being an independent predictor of late mortality. Prevalence of postoperative complications was similar between the ABO blood groups. Conclusions. In this large cohort of Nordic ATAAD patients, there were no associations between ABO blood group and surgical incidence or outcomes, including postoperative complications and survival.

中文翻译:

ABO血型不影响急性A型主动脉夹层的发生率或手术结局。

目标。为了评估ABO血型的分布和对术后急性A型主动脉夹层(ATAAD)患者术后结果的影响。设计。分析了构成北欧急性A型主动脉夹层联合体(NORCAAD)的八个北欧中心的1144例手术ATAAD患者。将O型血患者与非O型患者进行比较。血型的相对频率通过t分布进行评估,并针对加权比例进行了修改。进行多变量logistic回归以鉴定30天死亡率的独立预测因子。进行Cox回归分析以评估晚期死亡率的独立预测因子。结果。在NORCAAD注册中心的研究人群和背景人群之间,血型O的比例没有显着差异(40.6(95%CI 37.7-43.4)%对39.0(95%CI 39.0-39.0)%)。ABO血型与30天或晚期死亡风险没有任何显着变化相关,但A血型是晚期死亡的独立预测因子。ABO血型之间的术后并发症发生率相似。结论。在北欧ATAAD患者这一大队列中,ABO血型与手术发生率或结果(包括术后并发症和生存)之间没有关联。除了血型A是晚期死亡率的独立预测因素外,其他情况除外。ABO血型之间的术后并发症发生率相似。结论。在北欧ATAAD患者这一大队列中,ABO血型与手术发生率或结果(包括术后并发症和生存)之间没有关联。除了血型A是晚期死亡率的独立预测因素外,其他情况除外。ABO血型之间的术后并发症发生率相似。结论。在北欧ATAAD患者这一大队列中,ABO血型与手术发生率或结果(包括术后并发症和生存)之间没有关联。
更新日期:2020-04-23
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