The Immuno Polymorphism Database (IPD), https://www.ebi.ac.uk/ipd/, is a set of specialist databases that enable the study of polymorphic genes which function as part of the vertebrate immune system. The major focus is on the hyperpolymorphic major histocompatibility complex (MHC) genes and the killer-cell immunoglobulin-like receptor (KIR) genes, by providing the official repository and primary source of sequence data. Databases are centred around humans as well as animals important for food security, for companionship and as disease models. The IPD project works with specialist groups or nomenclature committees who provide and manually curate individual sections before they are submitted for online publication. To reflect the recent advance of allele sequencing technologies and the increasing demands of novel tools for the analysis of genomic variation, the IPD project is undergoing a progressive redesign and reorganisation. In this review, recent updates and future developments are discussed, with a focus on the core concepts to better future-proof the project.

中文翻译：

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IPD 项目：研究免疫系统基因多态性的集中资源。

免疫多态性数据库 (IPD)，https://www.ebi.ac.uk/ipd/，是一组专业数据库，可用于研究作为脊椎动物免疫系统一部分的多态性基因。通过提供官方存储库和序列数据的主要来源，重点关注超多态性主要组织相容性复合体 (MHC) 基因和杀伤细胞免疫球蛋白样受体 (KIR) 基因。数据库以人类和动物为中心，这些动物对粮食安全、陪伴和疾病模型都很重要。IPD 项目与专家小组或命名委员会合作，他们在提交在线出版之前提供并手动管理各个部分。为了反映等位基因测序技术的最新进展以及对基因组变异分析新工具日益增长的需求，IPD 项目正在进行逐步的重新设计和重组。在这篇评论中，讨论了最近的更新和未来的发展，重点关注核心概念，以更好地保证项目的未来发展。