Abstract Introduction Recumbency is a frequent symptom occurring throughout lactation. Its cause can be related to the energy or mineral metabolism, or to trauma or infectious diseases. We compared various clinical chemistry parameters between healthy and recumbent cows and between cows with different causes of recumbency and determined if hypocalcaemia manifests in later lactation. Material and Methods Recumbent (n = 32) and healthy (n = 32) German Holstein cows were studied. After clinical examination, a serum sample was taken to measure the concentrations of Mg, Ca, Fe, Na, K, Pi, β-hydroxybutyrate, total bilirubin, non-esterified fatty acids (NEFA), urea, and creatinine as well as activities of alkaline phosphatase, aspartate aminotransferase (AST), creatine kinase (CK), and γ-glutamyl transferase in recumbent cows > 5 d in milk and control cows matched for age, lactation number, and pregnancy stage. Results In recumbent cows, mean serum concentrations of NEFA, bilirubin, and CK were statistically higher, while those of Fe, K, and Pi were significantly lower. Parameters compared between different recumbency diagnoses showed some descriptive Fe, K, urea, and AST differences, but these were not statistically significant. Conclusion The results show that only a limited number of parameters have diagnostic besides therapeutic value. Although of minor importance in our study, hypocalcaemia should be considered a cause of recumbency, even outside the typical risk period of parturient paresis.

中文翻译：

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产奶第五天后卧卧和健康的德国荷斯坦奶牛的临床化学研究

摘要 简介 卧床是整个哺乳期的常见症状。其原因可能与能量或矿物质代谢有关，也可能与创伤或传染病有关。我们比较了健康和卧位奶牛之间以及不同卧位原因的奶牛之间的各种临床化学参数，并确定低钙血症是否在泌乳后期出现。材料和方法 研究了卧式 (n = 32) 和健康 (n = 32) 德国荷斯坦奶牛。临床检查后取血清样品测定镁、钙、铁、钠、钾、磷、β-羟基丁酸、总胆红素、非酯化脂肪酸（NEFA）、尿素和肌酐的浓度及活性卧式奶牛的碱性磷酸酶、天冬氨酸氨基转移酶 (AST)、肌酸激酶 (CK) 和 γ-谷氨酰转移酶 > 5 天的牛奶和对照奶牛的年龄、泌乳数和妊娠阶段相匹配。结果在卧位奶牛中，NEFA、胆红素和CK的平均血清浓度在统计学上较高，而Fe、K和Pi的平均血清浓度显着降低。不同卧床诊断之间的参数比较显示了一些描述性的 Fe、K、尿素和 AST 差异，但这些差异无统计学意义。结论 结果表明，除了治疗价值外，只有少数参数具有诊断价值。尽管在我们的研究中重要性较低，但低钙血症应被视为卧床的原因，即使在分娩性麻痹的典型风险期之外。而 Fe、K 和 Pi 则显着降低。不同卧床诊断之间的参数比较显示了一些描述性的 Fe、K、尿素和 AST 差异，但这些差异无统计学意义。结论 结果表明，除了治疗价值外，只有少数参数具有诊断价值。尽管在我们的研究中重要性较低，但低钙血症应被视为卧床的原因，即使在分娩性麻痹的典型风险期之外。而 Fe、K 和 Pi 则显着降低。不同卧床诊断之间的参数比较显示了一些描述性的 Fe、K、尿素和 AST 差异，但这些差异无统计学意义。结论 结果表明，除了治疗价值外，只有少数参数具有诊断价值。尽管在我们的研究中重要性较低，但低钙血症应被视为卧床的原因，即使在分娩性麻痹的典型风险期之外。