Whereas cancer cells are poor immunogens, some viruses are capable of eliciting powerful and lifelong immunity. Recombinant viruses and plasmid DNA encoding tumor-associated antigens can elicit powerful and specific immune responses that can be enhanced by the use of cytokines and costimulatory molecules. These immune responses have destroyed growing tumor cells in experimental animal models. For the first time, immunotherapeutic strategies that employ recombinant viruses are being tested in clinical trials with cancer patients.

中文翻译：

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新疫苗：构建可引发抗肿瘤免疫力的病毒。

癌细胞的免疫原性很差，而某些病毒却能够引发强大而终生的免疫力。重组病毒和编码与肿瘤相关的抗原的质粒DNA可以引发强大而特异性的免疫反应，可以通过使用细胞因子和共刺激分子来增强免疫反应。这些免疫反应破坏了实验动物模型中生长中的肿瘤细胞。首次在癌症患者的临床试验中对采用重组病毒的免疫治疗策略进行了测试。