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Morphological evolution of the vertebrate forebrain: From mechanical to cellular processes.
Evolution and Development ( IF 2.9 ) Pub Date : 2019-08-23 , DOI: 10.1111/ede.12308
Francisco Aboitiz 1, 2 , Juan F Montiel 3
Affiliation  

Although the cerebral hemispheres are among the defining characters of vertebrates, each vertebrate class is characterized by a different anatomical organization of this structure, which has become highly problematic for comparative neurobiology. In this article, we discuss some mechanisms involved in the generation of this morphological divergence, based on simple spatial constraints for neurogenesis and mechanical forces generated by increasing neuronal numbers during development, and the different cellular strategies used by each group to overcome these limitations. We expect this view to contribute to unify the diverging vertebrate brain morphologies into general, simple mechanisms that help to establish homologies across groups.

中文翻译:

脊椎动物前脑的形态演变:从机械过程到细胞过程。

尽管大脑半球是脊椎动物的定义特征之一,但每种脊椎动物类别都具有这种结构的不同解剖结构,这对于比较神经生物学来说已经成为很大的问题。在本文中,我们讨论了一些与这种形态差异有关的机制,这些机制基于神经发生的简单空间约束和发育过程中神经元数量的增加而产生的机械力,以及各组用来克服这些局限性的不同细胞策略。我们希望这种观点有助于将不同的脊椎动物脑形态统一为通用的简单机制,从而有助于在各个群体之间建立同源性。
更新日期:2019-08-23
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