Objective: Symptoms of ADHD are expected to be more difficult to treat in patients with a combination of ADHD and autism spectrum disorder (ASD) as opposed to only ADHD. Little evidence is available on the influence of ASD on the effects of pharmacotherapy in adults with ADHD. This study addresses this gap. Method: 60 adults with ADHD and comorbid ASD were selected from an outpatient clinic and compared with 226 adults from the same clinic with only ADHD. Similar treatment regimens were received. Results: Significant decreases in symptoms of ADHD were found in both groups. A diagnosis of ASD did not affect the reduction in symptoms of ADHD. No significant group differences in side effects or vital signs were found. Conclusion: Results show that medication for ADHD can effectively and safely be prescribed to patients with ADHD and comorbid ASD. Suggestions for future research are discussed.

中文翻译：

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成人自闭症谱系障碍的药物治疗：有效性和副作用。

目的：与仅多动症相反，多动症和自闭症谱系障碍（ASD）合并症的患者有望更难以治疗多动症的症状。关于ASD对患有ADHD的成年人的药物治疗的影响的证据很少。这项研究解决了这一差距。方法：从门诊中选择60名患有ADHD和合并症ASD的成年人，并与同一家仅患有ADHD的诊所中的226名成年人进行比较。收到了类似的治疗方案。结果：两组均发现ADHD症状明显减轻。ASD的诊断并不影响ADHD症状的减轻。在副作用或生命体征上未发现明显的群体差异。结论：结果表明，多动症并发自闭症患者可以有效，安全地开具多动症药物。