BACKGROUND Existed mathematical models of individual adaptation are mostly reductionist by nature. Researchers usually a priori consider the subject adapted basing only on the fact of continued or prolonged influence of the harmful factor. This paper describes a method that allows assessing the physiological adaptedness to experimental challenges on the basis of holistic approach and quantitative criteria. METHODS The suggested method comprises simple equations and incorporates into the model an indicator that differentiates functions in regard to their significance for determining physiological adaptedness considered as an outcome of the adaptive process. RESULTS The proposed empirical model affords the possibility of comparing subjects in respect to their resistance to several loads. Physiological parameters were differentiated with regard to their significance for assessing adaptedness. Two examples of animal adaptation to exercise after physical training and plant adaptogen administration are considered. CONCLUSION The calculated index of adaptedness is useful in that it replaces wordy descriptions of large tables that reveal alterations in numerous parameters of many subjects under study.

中文翻译：

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在生理学研究中估计适应性的定量方法。

背景技术现有的个体适应的数学模型本质上大多是归约论的。通常，研究人员通常仅根据有害因素持续或长期的影响来考虑是否适应该主题。本文介绍了一种方法，该方法可以基于整体方法和定量标准来评估对实验挑战的生理适应性。方法所建议的方法包括简单的方程式，并在模型中结合了一个指标，该指标根据功能在确定生理适应性方面的重要性来区分功能，这些功能被视为自适应过程的结果。结果提出的经验模型提供了比较对象在几种负载下的抵抗力的可能性。生理参数在评估适应性的意义方面有所不同。考虑了在体育锻炼和施用植物适应原后动物适应运动的两个例子。结论计算出的适应指数是有用的，因为它取代了大型表的冗长描述，揭示了许多研究对象的许多参数的变化。