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Electroconductive hydrogels for biomedical applications.
WIREs Nanomedicine and Nanobiotechnology ( IF 8.6 ) Pub Date : 2019-06-26 , DOI: 10.1002/wnan.1568
Han Lu 1 , Ning Zhang 2 , Mingming Ma 1
Affiliation  

Electroconductive hydrogels (EHs), combining both the biomimetic features of hydrogels and the electrochemical properties of conductive polymers and carbon-based materials, have received immense considerations over the past decade. The three-dimensional porous structure, hydrophilic properties, and regulatable chemical and physical properties of EH resemble the extracellular matrix in tissues, enable EHs a good matrix for cell growth, proliferation, and migration. Different from nonconductive hydrogels, EHs possess high electrical conductivity and electrochemical redox properties, which can be utilized to detect electric signals generated in biological systems, and also to supply electrical stimulation to regulate the activity and function of cells and tissues. Hence, this article provides a summary of the new development of EH for biomedical applications in the decade. We give a brief introduction of the design and synthesis of EHs, as well as current applications of EHs in biomedical fields, including cell culture, tissue engineering, drug delivery and controlled release, biosensors, and implantable bioelectronics. The development trends and challenges of EHs for biomedical applications are also discussed. This article is categorized under: Implantable Materials and Surgical Technologies > Nanomaterials and Implants Diagnostic Tools > Biosensing Therapeutic Approaches and Drug Discovery > Emerging Technologies.

中文翻译:

用于生物医学的导电水凝胶。

导电水凝胶(EHs)结合了水凝胶的仿生特征以及导电聚合物和碳基材料的电化学特性,在过去十年中受到了广泛的考虑。EH的三维多孔结构,亲水特性以及可调节的化学和物理特性类似于组织中的细胞外基质,使EHs成为细胞生长,增殖和迁移的良好基质。与非导电水凝胶不同,EH具有高电导率和电化学氧化还原特性,可用于检测生物系统中产生的电信号,还可提供电刺激以调节细胞和组织的活性和功能。因此,本文概述了十年来生物医学应用EH的新发展。我们简要介绍了EH的设计和合成,以及EH在生物医学领域的当前应用,包括细胞培养,组织工程,药物递送和控释,生物传感器以及可植入生物电子学。还讨论了生物医学应用EHs的发展趋势和挑战。本文归类于:可植入材料和外科技术>纳米材料和植入物诊断工具>生物传感治疗方法和药物发现>新兴技术。药物递送和控释,生物传感器和可植入生物电子产品。还讨论了生物医学应用EHs的发展趋势和挑战。本文归类于:可植入材料和外科技术>纳米材料和植入物诊断工具>生物传感治疗方法和药物发现>新兴技术。药物递送和控释,生物传感器和可植入生物电子产品。还讨论了生物医学应用EHs的发展趋势和挑战。本文归类于:可植入材料和外科技术>纳米材料和植入物诊断工具>生物传感治疗方法和药物发现>新兴技术。
更新日期:2019-11-01
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