Dengue is an emerging viral disease principally transmitted by the Aedes (Stegomyia) aegypti mosquito. It is one of the fastest-growing global infectious diseases, with 100-400 million new infections a year, and is now entrenched in a growing number of tropical megacities. Behind this rapid rise is the simple adaptation of Ae. aegypti to a new entomological niche carved out by human habitation. This review describes the expansion of dengue and explores how key changes in the ecology of Ae. aegypti allowed it to become a successful invasive species and highly efficient disease vector. We argue that characterizing geographic heterogeneity in mosquito bionomics will be a key research priority that will enable us to better understand future dengue risk and design control strategies to reverse its global spread.

中文翻译：

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登革热的全球扩张：埃及伊蚊如何引发了第一批大流行虫媒病毒。

登革热是一种主要由伊蚊（埃及伊蚊）传播的新兴病毒性疾病。它是全球增长最快的传染病之一，每年有100-400百万新感染，现在已经根植于越来越多的热带大城市。迅速崛起的背后是Ae的简单改编。埃及人居住的新昆虫学利基。这篇综述描述了登革热的扩大，并探讨了Ae生态学中的关键变化。埃及使其成为成功的入侵物种和高效的病媒。我们认为，表征蚊子生物组学中的地理异质性将是关键的研究重点，这将使我们能够更好地了解未来的登革热风险并设计控制策略来扭转其全球传播。