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DNA-Targeted Precision Medicine; Have we Been Caught Sleeping?
Trends in Cancer ( IF 18.4 ) Pub Date : 2016-12-27 , DOI: 10.1016/j.trecan.2016.11.002 William C Reinhold 1 , Anish Thomas 1, 2 , Yves Pommier 1
中文翻译:
DNA靶向精准医学;我们睡着了吗?
更新日期:2016-12-27
Trends in Cancer ( IF 18.4 ) Pub Date : 2016-12-27 , DOI: 10.1016/j.trecan.2016.11.002 William C Reinhold 1 , Anish Thomas 1, 2 , Yves Pommier 1
Affiliation
In the current drive to incorporate molecular markers into treatment selection for precision medicine, there has been a significant and, we believe, ill-advised omission of the large and routinely used group of drugs whose mechanism of action is DNA damage.
中文翻译:
DNA靶向精准医学;我们睡着了吗?
在将分子标记物纳入精密医学治疗选择的当前驱动中,我们认为,作用机制为DNA损伤的大量常规药物存在重大且不明智的遗漏。