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Using Zebrafish to Study Pathways that Regulate Hematopoietic Stem Cell Self-Renewal and Migration.
Stem Cell Reports ( IF 5.9 ) Pub Date : 2017-06-06 , DOI: 10.1016/j.stemcr.2017.05.018
Avik Choudhuri 1 , Eva M Fast 1 , Leonard I Zon 2
Affiliation  

This perspective describes the usefulness of zebrafish as a model to study interaction of hematopoietic stem cells with the associated niche in vivo, explains how such interactions influence regeneration, migration, and clonality of HSCs, and defines their fate during differentiation.

中文翻译:

使用斑马鱼研究调节造血干细胞自我更新和迁移的途径。

这一观点描述了斑马鱼作为研究造血干细胞与体内相关生态位相互作用的模型的有用性,解释了这种相互作用如何影响 HSC 的再生、迁移和克隆性,并定义了它们在分化过程中的命运。
更新日期:2019-11-01
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