The pigmentation of skin and hair in mammals is driven by the creation within melanocytes of melanosomes, a specialized pigment-producing organelle, and the subsequent intercellular transfer of this organelle to keratinocytes. This latter process is absolutely required for visible pigmentation and effective photo-protection because it serves to disperse the pigment in skin and hair. Therefore, the transfer of melanosomes from the melanocyte to the keratinocyte is as important for the biological endpoint of mammalian pigmentation as the biogenesis of this fascinating organelle. Here we review new findings that shed light on, and raise additional questions about, the mechanism of this enigmatic process.

中文翻译：

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黑素体转移：最好是给予和接受。

哺乳动物皮肤和毛发的色素沉着是由黑素体（一种专门的产生色素的细胞器）在黑素细胞内产生，以及随后该细胞器向角质形成细胞的细胞间转移所驱动的。后一个过程对于可见色素沉着和有效的光保护是绝对需要的，因为它有助于将色素分散在皮肤和头发中。因此，黑色素体从黑色素细胞转移到角质形成细胞对于哺乳动物色素沉着的生物学终点与这种迷人细胞器的生物发生一样重要。在这里，我们回顾了一些新发现，这些发现阐明了这个神秘过程的机制，并提出了其他问题。