The conventional toroidal coil in centrifugal countercurrent chromatography has a low level of stationary phase retention, since a half of each helical turn is entirely occupied by the mobile phase. In order to cope with this problem, several new column designs including zigzag, saw-tooth, and figure-8 patterns have been introduced, and their performance was compared in terms of retention of the stationary phase (Sf), peak resolution (Rs), theoretical plate number (N), and column pressures. Overall results of experiments indicate that the figure-8 column yields the highest Rs when the lower phase is used as the mobile phase. Since the column pressure of all these new columns are much lower than that in the traditional toroidal coil column, the separation efficiency can be improved using a long separation column without a risk of column damage by high back pressure.

中文翻译：

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离心逆流色谱的新设计：V. 各种色谱柱配置性能的比较研究

离心逆流色谱中的传统环形线圈具有较低的固定相保留水平，因为每个螺旋圈的一半完全被流动相占据。为了解决这个问题，我们引入了多种新的色谱柱设计，包括锯齿形、锯齿形和 8 字形图案，并在固定相保留 (Sf)、峰分辨率 (Rs) 方面比较了它们的性能、理论塔板数 (N) 和柱压。实验的总体结果表明，当使用下相作为流动相时，图 8 色谱柱产生最高的 Rs。由于所有这些新柱的柱压都远低于传统环形线圈柱的柱压，