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Genome-wide scan for visceral leishmaniasis susceptibility genes in Brazil.
Genes and Immunity ( IF 5 ) Pub Date : 2006-11-24 , DOI: 10.1038/sj.gene.6364357
S E Jamieson 1 , E N Miller , C S Peacock , M Fakiola , M E Wilson , A Bales-Holst , M-A Shaw , F Silveira , J J Shaw , S M Jeronimo , J M Blackwell
Affiliation  

A genome-wide scan was conducted for visceral leishmaniasis (VL) in Brazil. Initially, 405 markers were typed in 22 multicase pedigrees (28 nuclear families; 174 individuals; 66 affected). Non-parametric multipoint analysis detected nine chromosomal regions with provisional evidence (logarithm of the odds (LOD) scores 0.95-1.66; 0.003

中文翻译:

全基因组扫描内脏利什曼病易感基因在巴西。

对巴西的内脏利什曼病(VL)进行了全基因组扫描。最初,在22个多病例谱系(28个核心家庭; 174个个体; 66个受影响)中输入了405个标记。非参数多点分析检测了九个具有临时证据的染色体区域(对数对数(LOD)得分0.95-1.66; 0.003
更新日期:2019-11-01
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