Na⁺/K⁺-pump is an electrogenic transmembrane ATPase located in the outer plasma membrane of cells. The Na⁺/K⁺-ATPase pumps 3 sodium ions out of cells while pumping 2 potassium ions into cells. Both cations move against their concentration gradients. This enzyme’s electrogenic nature means that it has a chronic role in stabilizing the resting membrane potential of the cell, in regulating the cell volume and in the signal transduction of the cell. This review will mainly consider the role of the Na⁺/K⁺-pump in neurons, with an emphasis on its role in modulating neurotransmitter receptor. Most of the literature on the modulation of neurotransmitter receptors refers to the situation in the mammalian nervous system, but the position is likely to be similar in most, if not all, invertebrate nervous systems.

中文翻译：

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Na + / K +-泵和神经递质膜受体。

Na ⁺ / K ^+-泵是一种位于细胞外质膜上的电跨膜ATPase。Na ⁺ / K ⁺ -ATPase将3个钠离子泵出细胞，同时将2个钾离子泵入细胞。两种阳离子均沿其浓度梯度移动。这种酶的电性性质意味着它在稳定细胞的静息膜电位，调节细胞体积和细胞信号转导中具有长期作用。这篇评论将主要考虑Na ⁺ / K ^+的作用泵浦神经元，重点在于其在调节神经递质受体中的作用。关于神经递质受体调节的大多数文献都涉及哺乳动物神经系统中的情况，但是在大多数（如果不是全部）无脊椎动物神经系统中，其位置可能相似。