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Primary HIV infection in patients with acute hepatitis B: a report of two cases.
Antiviral Therapy ( IF 1.2 ) Pub Date : 2017-10-13 , DOI: 10.3851/imp3201
Francesca Binda 1 , Elisa Monge 1 , Francesco R Simonetti 2 , Nadia Zanchetta 3 , Massimo Galli 1, 4 , Laura Milazzo 4 , Mario Corbellino 4 , Spinello Antinori 1, 4
Affiliation  

We describe two patients admitted to our institution with a diagnosis of sexually acquired acute hepatitis B who also had underlying hyper acute HIV infection. Both individuals reported high rates of condomless sex. Antiviral therapy active against HBV and HIV was started within days after diagnosis. Treatment was well tolerated and led to a rapid control of both infections and hepatitis B surface antibody seroconversion. The efficacy and safety of contemporary antiretroviral drug combinations suggest that treatment of acute HIV infection is feasible in patients with acute hepatitis B.

中文翻译:

急性乙型肝炎患者的原发性HIV感染:两例报道。

我们描述了两名入院并诊断为性获得性急性乙型肝炎的患者,这些患者也患有潜在的高度急性HIV感染。两个人都报告无避孕套性行为的发生率很高。诊断后数天内就开始了对HBV和HIV有效的抗病毒治疗。治疗耐受性良好,可快速控制感染和乙型肝炎表面抗体的血清转化。现代抗逆转录病毒药物组合的疗效和安全性提示,急性乙型肝炎患者治疗急性HIV感染是可行的。
更新日期:2020-08-21
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