According to current recommendations diagnosis and management of HCV infection need detection and quantification of nucleic acids. In the era of direct-acting antivirals (DAA) it is essential to develop an inexpensive and simple method replacing polymerase chain reaction. Since there is no available data on HCV core antigen (HCVcAg) versus HCV RNA kinetics in the early phase of treatment with DAA, we carried out this study to evaluate the possible application of HCVcAg quantitative measurement for management of HCV infection.

中文翻译：

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HCV核心抗原的定量检测，可用于HCV感染患者的无干扰素治疗。

根据当前的建议，HCV感染的诊断和管理需要核酸的检测和定量。在直接作用抗病毒药物（DAA）时代，开发一种廉价且简单的方法来取代聚合酶链反应至关重要。由于在DAA治疗的早期阶段尚无关于HCV核心抗原（HCVcAg）与HCV RNA动力学的可用数据，因此我们进行了这项研究，以评估HCVcAg定量检测在HCV感染管理中的可能应用。