Purpose: This study was designed to assess memory, imitation of motor actions and motor performance by 12 children (age range 40–151 months) with Angelman syndrome (AS), a rare neurogenetic disorder associated with learning and memory impairments. Methods: Children’s functioning was assessed at several time points over a 3-month period. Results: Memory and motor performance tests had acceptable test-retest and inter-rater reliability whereas the motor imitation test did not. Children were able to recall action sequences after a 24-h delay. Memory and motor performance scores were correlated with children’s chronological age and raw scores on subdomains of the Vineland-II. Conclusions: These behavioral tests require further development and evaluation but may show promise to accompany standardized assessments that are currently in use with children with AS.

目的：本研究旨在评估12名患有Angelman综合征（AS）的儿童（年龄在40-151个月之间）的记忆，模仿动作行为和运动表现，这是一种与学习和记忆障碍相关的罕见神经遗传性疾病。方法：在三个月的多个时间点评估儿童的功能。结果：记忆和电机性能测试具有可接受的重测和评估者间可靠性，而电机模仿测试则没有。在延迟24小时后，孩子们能够回忆起动作序列。记忆和运动成绩与儿童的年龄和在Vineland-II子域上的原始分数相关。结论：这些行为测试需要进一步的开发和评估，但可能显示出有望与AS儿童一起使用的标准化评估相结合。