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Emergency Department Initiation of Buprenorphine for Opioid Use Disorder: Current Status, and Future Potential.
CNS Drugs ( IF 6 ) Pub Date : 2019-12-01 , DOI: 10.1007/s40263-019-00667-7
Lindsay Fox 1 , Lewis S Nelson 1
Affiliation  

Patients experiencing the consequences of opioid use often present to the emergency department (ED) at times of crisis, such as following overdose or when in withdrawal. This highlights the important role of the ED in recognizing opioid use disorder and engaging these patients into ongoing treatment. Given the limited ability of the healthcare system to provide timely addiction treatment, initiation of therapy in the ED, with referral to long-term care, is associated with improved outcomes. The primary evidence-based treatment used in EDs for this indication is buprenorphine. Although clinicians may find the initiation of buprenorphine therapy daunting, it is straightforward and well-tolerated, and many of the barriers are surmountable. This article addresses these barriers, which include stigma, complicated pharmacology, and confusing regulations, and provides a basis for the use of buprenorphine in acute care clinical practice.

中文翻译:

阿片类药物使用急症的丁丙诺啡急诊科启动:现状和未来潜力。

遇到阿片类药物使用后果的患者通常在危急时刻(例如服药过量或停药后)出现在急诊室。这突出了ED在识别阿片类药物使用障碍并使这些患者参与正在进行的治疗中的重要作用。鉴于医疗保健系统提供及时成瘾治疗的能力有限,因此在急诊中开始治疗并转诊至长期护理会改善预后。ED中用于此指征的主要循证治疗方法是丁丙诺啡。尽管临床医生可能会感到丁丙诺啡治疗的开始令人生畏,但这是直接且耐受性良好的,许多障碍是可以克服的。本文解决了这些障碍,包括污名,复杂的药理学和令人困惑的法规,
更新日期:2019-11-01
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