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The reproducibility of measurements using a standardization phantom for the evaluation of fractional anisotropy (FA) derived from diffusion tensor imaging (DTI).
Magnetic Resonance Materials in Physics Biology and Medicine ( IF 2.3 ) Pub Date : 2019-09-24 , DOI: 10.1007/s10334-019-00776-w
Mitsuhiro Kimura 1 , Hidetake Yabuuchi 1 , Ryoji Matsumoto 2 , Koji Kobayashi 2 , Yasuo Yamashita 2 , Kazuya Nagatomo 1 , Ryoji Mikayama 1 , Takeshi Kamitani 3 , Koji Sagiyama 3 , Yuzo Yamasaki 3
Affiliation  

OBJECTIVES It is necessary to standardize the examination procedure and diagnostic criteria of diffusion tensor imaging (DTI). Thus, the purpose of this study was to examine the reproducibility of measurements using a standardization phantom composed of different fibre materials with different fibre densities (FDs) for the evaluation of fractional anisotropy (FA) derived from DTI. MATERIALS AND METHODS Two types of fibre materials wrapped in heat-shrinkable tubes were used as fibre phantoms. We designed fibre phantoms with three different FDs of each fibre material. The standardization phantom was examined using DTI protocol six times a day, and each examination session was repeated once a month for 7 consecutive months. Fibre tracking was performed by setting regions of interest in the FA map, and FA was measured in each fibre phantom. Coefficients of variation (CVs) were used to evaluate the inter-examination reproducibility of FA values. Furthermore, Bland-Altman plots were used to evaluate the intra-operator reproducibility of FA measurements. RESULTS All CVs for each fibre phantom were within 2% throughout the 7-month study of repeated DTI sessions. The high intra-operator reproducibility of the FA measurement was confirmed. DISCUSSION High reproducibility of measurements using a standardization phantom for the evaluation of FA was achieved.

中文翻译:

使用标准化体模评估源自扩散张量成像(DTI)的分数各向异性(FA)的测量结果的可重复性。

目的有必要规范弥散张量成像(DTI)的检查程序和诊断标准。因此,本研究的目的是使用由不同纤维密度(FDs)组成的不同纤维材料组成的标准化体模检查测量的可重复性,以评估源自DTI的分数各向异性(FA)。材料与方法使用两种类型的包裹在热缩管中的纤维材料作为纤维模型。我们设计了每种光纤材料具有三个不同FD的光纤模型。每天使用DTI协议检查标准化体模六次,每个检查环节每月重复一次,连续7个月。通过在FA图中设置感兴趣的区域来执行光纤跟踪,并在每个光纤模型中测量FA。变异系数(CV)用于评估FA值的检验间可重复性。此外,使用Bland-Altman图来评估FA测量值在操作员内的可重复性。结果在重复DTI会话的7个月研究中,每个光纤模型的所有CV均在2%以内。可以确认FA测量值具有较高的操作员内部重复性。讨论实现了使用标准化体模评估FA的测量结果的高重复性。可以确认FA测量值具有较高的操作员内部重复性。讨论实现了使用标准化体模评估FA的测量结果的高重复性。可以确认FA测量值具有较高的操作员内部重复性。讨论实现了使用标准化体模评估FA的测量结果的高重复性。
更新日期:2020-04-22
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