The prospect of healthcare systems offering population-based preventive genomic testing to all adults is becoming feasible. Some single-payer or state-funded healthcare systems are already considering offering universal testing as part of routine care. In countries with public healthcare systems, there is a unique opportunity to provide such testing in the form of a national screening program, following existing national population health-screening frameworks. This paradigm, if achievable, could help deliver a degree of testing quality and equity-of-access that may not be possible in private-payer or direct-to-consumer models, to maximize prevention and health benefits. Here, we outline some of the major challenges ahead in considering this prospect and discuss the research that is helping shape the future direction in Australia and elsewhere.

中文翻译：

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医疗保健系统资助的预防性基因组筛查：澳大利亚和其他单一付款人系统面临的挑战

为所有成年人提供基于人群的预防性基因组检测的医疗保健系统的前景正在变得可行。一些单一付款人或国家资助的医疗保健系统已经在考虑将普遍检测作为常规护理的一部分。在拥有公共医疗保健系统的国家，有一个独特的机会可以按照现有的国家人口健康筛查框架以国家筛查计划的形式提供此类检测。如果可以实现，这种范式可以帮助提供一定程度的测试质量和公平获取，这在私人付款人或直接面向消费者的模式中可能是不可能的，从而最大限度地提高预防和健康效益。在这里，我们概述了在考虑这一前景时面临的一些主要挑战，并讨论了有助于塑造澳大利亚和其他地方未来发展方向的研究。