Multidrug transporters are important and interesting molecular machines that extrude a wide variety of cytotoxic drugs from target cells. This review summarizes novel insights in the energetics and mechanisms of bacterial ATP-binding cassette multidrug transporters as well as recent advances connecting multidrug transport to ion and lipid translocation processes in other membrane proteins.

中文翻译：

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ABC出口商中的能量耦合。

多药转运蛋白是重要且有趣的分子机器，可从靶细胞中挤出多种细胞毒性药物。这篇综述总结了细菌ATP结合盒多药转运蛋白的能量学和机制方面的新见解，以及将多药转运与其他膜蛋白中的离子和脂质转运过程联系起来的最新进展。