当前位置: X-MOL 学术Trends Microbiol. › 论文详情
Our official English website, www.x-mol.net, welcomes your feedback! (Note: you will need to create a separate account there.)
Microbial endocrinology and infectious disease in the 21st century.
Trends in Microbiology ( IF 15.9 ) Pub Date : 2004-01-01 , DOI: 10.1016/j.tim.2003.11.004
Mark Lyte 1
Affiliation  

More than 70 years ago, a new age in endocrinology was just beginning with the first purification of a hormone, adrenaline. As early as 1930, almost immediately following its first use, cases of adrenaline-associated sepsis were reported. From this time, there have been reports associating the elaboration of neuroendocrine hormones, such as adrenaline, with infectious disease. The most widely accepted theory to explain the ability of hormones to influence the course of infection involves the suppression of the immune system. The theory that the infectious microorganism itself might be equally responsive to the host's neuroendocrine environment has not been considered. It is the intent of this article to introduce a new perspective to the current understanding of the factors that mediate the ability of bacteria to cause disease, and to demonstrate that neuroendocrinology and microbiology intersect to form the interdisciplinary field of microbial endocrinology.

中文翻译:

21世纪的微生物内分泌学和传染病。

70多年前,内分泌学的新时代才刚刚开始首次纯化激素肾上腺素。早在1930年,就报道了肾上腺素相关败血症的病例,几乎是在首次使用后。从那时起,已有报道将神经内分泌激素如肾上腺素的加工与传染病相关联。解释激素影响感染过程的能力的最广泛接受的理论涉及免疫系统的抑制。尚未考虑传染性微生物本身可能对宿主的神经内分泌环境具有同等反应的理论。本文的目的是为当前对介导细菌致病能力的因素的理解提供一个新的视角,
更新日期:2019-11-01
down
wechat
bug