Oxidation of melatonin by Fenton reagents as well as with hypochlorous acid or oxoferryl hemoglobin has been investigated. Analysis of products by low resolution/mass spectra (MS), high resolution/MS, 1H-nuclear magnetic resonance (NMR), 13C-NMR, correlated spectroscopy (COSY) and heterocorrelated spectroscopy (HETCOR) 2D NMR reveals the formation of a single mono-oxygenated product under all conditions and unequivocally assigns the N-[2-(5-methoxy-2-oxo-2,3-dihydro-1H-indol-3-yl)-ethyl]-acetamide structure, which had not been previously considered.

中文翻译：

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褪黑激素：其非酶性单氧化代谢物的结构特征。

已经研究了Fenton试剂以及次氯酸或草酰氧血红蛋白对褪黑激素的氧化作用。通过低分辨率/质谱（MS），高分辨率/ MS，1H核磁共振（NMR），13C-NMR，相关光谱（COSY）和异相关光谱（HETCOR）对产品进行分析2D NMR揭示了单个分子的形成在所有条件下均单加氧，并明确分配N- [2-（5-甲氧基-2-氧代-2,3-二氢-1H-吲哚-3-基）-乙基]-乙酰胺结构以前考虑过。