This study describes the methods and results of superparamagnetic iron oxide nanoparticle (SPION) labeling and magnetic resonance imaging (MRI) tracking of human embryonic stem cell-derived photoreceptor precursors transplanted into the subretinal space of Royal College of Surgeons rats. SPION labeling and MRI tracking provide information about the biodistribution of transplanted photoreceptor precursors, which is necessary for improving the functional benefits of cell therapy for degenerative retinal diseases.

中文翻译：

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磁共振成像的光感受器前体的磁性氧化铁纳米颗粒标记。

这项研究描述了超顺磁性氧化铁纳米粒子（SPION）标记和磁共振成像（MRI）跟踪移植到皇家外科医学院大鼠视网膜下空间的人胚胎干细胞衍生的感光受体前体的方法和结果。SPION标记和MRI跟踪提供了有关移植的感光受体前体生物分布的信息，这对于改善细胞治疗视网膜变性疾病的功能益处是必需的。