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Optimal Vector-borne Disease Screening in Dogs Using Both Serology-based and Polymerase Chain Reaction-based Diagnostic Panels.
Veterinary Clinics of North America: Small Animal Practice ( IF 1.9 ) Pub Date : 2019-04-13 , DOI: 10.1016/j.cvsm.2019.02.011
Linda Kidd 1
Affiliation  

Vector-borne disease and idiopathic immune-mediated disease present similarly. Diagnostic panels that include multiple organisms help detect infection and identify coinfections. Comprehensive diagnostic panels that combine polymerase chain reaction (PCR) and serology should be used in initial screening to maximize sensitivity and identify infection. Repeat testing using PCR is warranted in dogs at high risk of infection with organisms that circulate in blood in low numbers or intermittently. Convalescent serologic testing can help diagnose acute infection. This article discusses the pathophysiology and epidemiology of the organisms, panel selection, and how to recognize when more aggressive testing for an organism is warranted.

中文翻译:

使用基于血清学和基于聚合酶链反应的诊断面板对犬进行最佳的媒介传播疾病筛查。

媒介传播疾病和特发性免疫介导的疾病相似。包含多种生物的诊断面板可帮助检测感染并鉴定合并感染。最初的筛查应使用结合了聚合酶链反应(PCR)和血清学的综合诊断小组,以最大程度地提高敏感性并鉴定感染。在高感染被少量或间歇性血液循环的生物感染的狗中,有必要使用PCR进行重复测试。康复期血清学检查可以帮助诊断急性感染。本文讨论了生物的病理生理学和流行病学,专家组选择,以及当需要对生物进行更积极的检测时如何识别。
更新日期:2019-11-01
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