Hepatitis B virus (HBV) infection is one of the major health issues in the world presently with high tendency of leading to hepatocarcinoma, cirrhosis, and liver cancer, especially if not properly managed. It has been estimated that there are about 2 billion people with a serological profile of HBV infection, and 360 million patients worldwide living with chronic HBV-associated liver disease, hence the need to find an efficient and precise diagnosis technique to drive a robust treatment for Hepatitis B virus cannot be over emphasized. The emergence of analytical device like biosensor which combines biological and physicochemical element to detect HBV in screened samples has been very helpful in providing a timely intervention to tame this virus. This review focuses on the current state of biosensor researches with respect to various in-depth application of gold nanoparticle for the detection of hepatitis B virus (HBV).

中文翻译：

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金纳米颗粒和乙型肝炎病毒。

乙型肝炎病毒（HBV）感染是世界上主要的健康问题之一，目前极有可能导致肝癌，肝硬化和肝癌，尤其是如果管理不当的话。据估计，全球约有20亿人患有HBV感染的血清学特征，全球有3.6亿患者患有慢性HBV相关性肝病，因此需要寻找一种有效且精确的诊断技术来为患者提供强有力的治疗方法乙肝病毒不能过分强调。结合了生物学和物理化学元素的生物传感器等分析设备的出现，对检测出的样本中的HBV产生了很大的帮助，为及时驯服这种病毒提供了帮助。